Huilin Li Publications:

Chavan M, Chen Z, Li G, Schindelin H, Lennarz WJ, and Li H. Dimeric organization of the yeast oligosaccharyl transferase complex. Proc Natl Acad Sci USA 103, 8947-8952 (2006).   PubMed   Full Text

Lazarov VK, Fraering PC, Ye W, Wolfe MS, Selkoe DJ, and Li H. Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores. Proc Natl Acad Sci USA 103, 6889-6894 (2006).   PubMed   Full Text

Lin G, Hu GQ, Tsu C, Kunes Y, Li H, Dick L, Li, P, Chen ZQ, Zwickl P, Weich N, and Nathan C. Mycobacterium tuberculosis prcBA Genes Encode a Gated Proteasome with Broad Oligopeptide Specificity Mol Microbiol 59, 1405-1416, (2006).   PubMed Hu GQ, Lin G, Wang M, Dick L, Xu R, Nathan C, and Li H. Structure of the Mycobacterium tuberculosis Proteasome and Mechanism of Inhibition by a Peptidyl Boronate. Mol Microbiol 59, 1417-1428 (2006).   PubMed PDB files: 2FHG, 2FHH   Jmol viewer For a summary read the BNL Press Release of March 6, 2006

Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, and Shi Y. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature 437, 831-7, (2005).   PubMed PDB file: 2A5Y   Jmol viewer

Speck C, Chen ZQ, Li H, and Stillman B. ATPase-dependent, cooperative binding of ORC and Cdc6p to origin DNA. Nature Struct Mol Biol 12, 965-971, (2005).   PubMed Darwin KH, Lin G, Chen Z, Li H, and Nathan, CF. Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue. Mol Microbiol 55(2), 561-571 (2005).   PubMed <-- click on icon for larger view of Molecular Mirobiology Cover

Liu W, Crocker E, Zhang W, Elliott JI, Luy B, Li H, Aimoto S, Smith SO. Structural role of glycine in amyloid fibrils formed from transmembrane alpha-helices. Biochemistry 44(9), 3591-3597 (2005).   PubMed

Surana NK, Grass S, Hardy GG, Li H, Thanassi DG, and Geme JW III. Evidence for conservation of architecture and physical properties of Omp85-like proteins throughout evolution Proc Natl Acad Sci USA 101(40), 14497-14502 (2004).   PubMed   Full Text

Li H, Qian L, Chen Z, Thibault D, Liu G, Liu TB, and Thanassi DG. The outer membrane usher forms a twin-pore secretion complex. J Mol Biol 344(5), 1397-1407 (2004).   PubMed For a summary read the BNL Press Release of November 9, 2004

Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, and Downing KH. The binding mode of Epothilone A on alpha,beta-tubulin by electron crystallography Science 305, 866-869 (2004).   PubMed PDB file: 1TVK   Jmol viewer For a summary read the BNL Press Release of August 5, 2004

Chen Z, Green TJ, Luo M, and Li H. Visualizing the RNA molecule in the bacterially expressed vesicular stomatitis virus nucleoprotein-RNA complex. Structure (Camb.) 12(2), 227-35 (2004).   PubMed

Wei Y, Li H, and Fu D. Oligomeric state of the Escherichia coli metal transporter YiiP. J Biol Chem Jul 16 [Epub ahead of print] (2004).   PubMed   Full Text

Liu T, Diemann E, Li H, Dress AW, and Muller A. Self-assembly in aqueous solution of wheel-shaped Mo154 oxide clusters into vesicles. Nature 426, 59-62 (2003).   PubMed

Li HL, Shi D, Ren G, Sui HX, Chen DH, and Wang DN. Cryo-electron microscopy of biological macromolecules. In: Recent Progress in Transmission Electron Microscopy. Edited by HQ Ye and YM Wang. Science Press 114-148, (2003).

Poirier MA, Li H, Macosko J, Cai S, Amzel M, and Ross CA. Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. J Biol Chem 277, 41032-7 (2002).   PubMed   Full Text

Li H, DeRosier DJ, Nicholson WV, Nogales E, and Downing KH. The microtubule structure at 8Å resolution. Structure 10, 1317-28 (2002).   PubMed

Downing KH, and Li H. Accurate recording and measurement of electron diffraction data in structural and difference Fourier studies of proteins. Microscopy and Microanalysis 7, 407-17 (2001).

	Löwe J, Li HL, Downing KH, and Nogales E. Refined structure of alpha beta-tubulin at 3.5Å resolution. J Mol Biol 313, 1045-57 (2001).   PubMed PDB file: 1JFF   Jmol viewer
	Li HL, Sui HX, Ghanshani S, Lee S, Walian PJ, Wu CL, Chandy KG, and Jap BK. Two-dimensional crystallization and projection structure of KcsA potassium channel. J Mol Biol 282, 211-6 (1998).   PubMed
	Li HL, Lee S, and Jap BK. Molecular design of aquaporin-1 water channel as revealed by electron crystallography. Nature Struct Biol 4, 263-5 (1997).   PubMed

Spencer RH, Sokolov Y, Li HL, Takenaka B, Milici AJ, Aiyar J, Nguyen A, Park H, Jap BK, Hall JE, and Chandy KG. Purification, visualization, and biophysical characterization of Kv1.3 tetramers. J Biol Chem 272, 2389-95 (1997).   PubMed   Full Text

Jap BK, and Li HL. Structure of osmo-regulated H2O-channel, AQP-CHIP, in projection at 3.5Å resolution. J Mol Biol 251, 413 (1995).   PubMed

Li XZ, Li HL, Frey F, Steurer W, and Kuo KH. Structural models of high-order approximants of the Al-Mn-Pd decagonal quasicrystal. Phil Mag B 71, 1101-1110 (1995).

Li HL, Zhang Z, and Kuo KH. Experimental Amman-line analysis of phasons in the Al-Cu-Co-Si decagonal quasicrystal. Phys Rev B 50, 3645-7 (1994).   Abstract   Full Text

Li HL, and Kuo KH. Some new crystalline approximants of Al-Pd-Mn quasicrystals. Phil Mag Lett 70, 55 (1994).

Zhang Z, Li HL, and Kuo KH. Stable decagonal Al-Cu-Co-Si phase, a phason perturbed quasiperiodic crystal. Phys Rev B 48, 6949-51 (1993).   Abstract   Full Text

Li HL, Zhang YW, Zou HM, and Wang RH. A transmission electron microscopy study of ferroelectric domains in a modified lead zirconate titanate ceramic. J Phys Condensed Matters 5, 5037 (1993).

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