Biology Seminars in 1998
Thursday January 22 3:00	Compatibility of structural information inferred from mutagenesis and x-ray crystallography for various cholinesterase complexes Avigdor Shafferman, Israel Institute of Biological Research Host: Joel Sussman
Thursday January 29 3:45	Natural genetic transformation in Streptococcus pneumoniae: regulation of competence by peptide pheromones Donald Morrison, University of Illinois at Chicago Host: Sandy Lacks
Monday February 2 12:00	Design and synthesis of novel anticonvulsants (rational drug design, molecular modeling and molecular biology) Puthucode N. Ramanan, University of Saskatchewan Host: Wally Mangel
Friday February 6 11:00	A new protein surface-feature database for comparing structure-function relationships within and between protein families Richard Fine, Paradygm Technologies & Columbia University Host: Bob Sweet
Thursday February 19 3:00	Acyl carrier protein: The key to soluble diiron desaturase catalysis Brian G. Fox, Enzyme Institute, University of Wisconsin-Madison Host: John Shanklin
Wednesday February 26 3:45	The 2.5 Å structure of the HIV-1 envelope glycoprotein, gp120, in complex with CD4 and a neutralizing antibody Peter Kwong, Columbia University Host: Cathy Lawson
Wednesday March 4 3:45	Comparative structure modeling for genome products Andrej Sali, Rockefeller University Host: Joel Sussman
Thursday March 19 3:45	Cryoelectron microscopy of the calcium pump from sarcoplasmic reticulum at 8 Å resolution David Stokes, NYU School of Medicine Host: Michael Becker
Monday March 23 11:00	Transcription modulation by the Adenovirus E1A 243R oncoprotein Gang Wang, Tulane University Medical Center Host: Carl Anderson
Wednesday March 26 3:45	Conformational changes in serine proteinase inhibitors (serpins) Arthur Lesk, University of Cambridge Clinical School Host: Joel Sussman
Monday April 6 12:00	Mapping the rice genome and the International Rice Genome Sequencing Project Dr. Takuji Sasaki, Director, Rice Genome Research Program, Tsukuba Host: Ben Burr
April 8, 1998 Workshop	United States Workshop on Rice Genomic Sequencing USDA Headquarters Organizers: Benjamin Burr (BNL) and Ralph Quatrano (U North Carolina, Chapel Hill)
Thursday April 9 3:45	Oncological and hematological aspects of the Chernobyl accident Daniil Gluzman, M.D., Head, Laboratory of Immunocytochemistry and Oncohematology, R.E. Kavetsky Institute of Experimental Pathology, National Academy of Science of Ukraine Host: John Dunn
Thursday April 16 11:00	Biological macromolecular structure visualization with RasMol and Chime Eric Martz University of Massachusetts Host: Joel Sussman
Wednesday April 22 4:00	Cloning a Human Virus Receptor Gene: Implications for Gene Therapy Paul I. Freimuth Biology Department, BNL 336th Brookhaven Lecture
Thursday April 23 3:45	The solving of crystal structures of small proteins by three-beam diffraction Kerstin Hölzer and Klaus Schroer, Universität Karlsruhe Host: Bob Sweet
Tuesday April 28 12:00	Calcium modulation of photoreceptor guanylate cyclases Rafal Goraczniak, U. of Medicine and Dentistry of New Jersey Host: Carl Anderson
Monday May 4 12:00	Genomic instability induced by irradiated male germ-cells as revealed by the Medaka test system Akihiro Shima, University of Tokyo Host: Richard Setlow
Thursday May 21 3:45	DNA repair and apoptotic gene mutations which affect mammalian radiation sensitivity Eric Hendrickson, Brown University Host: Carl Anderson
May 14,1998 Workshop	Exploring and Presenting Macromolecular Structures Using Chime Eric Martz, University of Massachusetts Organizer: Nancy Manning, Protein Data Bank
Thursday May 21 3:45	DNA repair and apoptotic gene mutations which affect mammalian radiation sensitivity Eric Hendrickson, Brown University Host: Carl Anderson
Thursday May 28 3:45	Sensing mode atomic force microscopy Chengpu Wang, SUNY Stony Brook Host: Paul Hough
Thursday June 4 3:45	Chemical imaging of biological cells and tissues with synchrotron infrared microspectroscopy Lisa M. Miller, Albert Einstein College of Medicine Host: Bob Sweet
Friday June 12 11:00	Probing the water oxidation chemistry of Photosystem II Gary Brudvik, Yale University Host: Michael Becker
Friday August 7 11:00	How light activates rhodopsin: Structure function studies of the prototypical G protein-coupled receptor Steven O. Smith, SUNY Stony Brook Host: F. William Studier
Thursday August 20 3:45	Understanding RNA viruses in the postgenomic era Alexander E. Gorbalenya, Cancer Research Facility Frederick MD Host: F. William Studier
Monday August 24 12:00	Three molecular motors catalyze T7 DNA translocation into E. coli Ian Molineux, University of Texas, Austin Host: John Dunn
Wednesday September 9 1:00 pm	Good, bad, or ugly, MAD phasing is powerful, and what's new about the old cytochrome c ? Ruslan Sanishvili, Structural Biology Center, Argonne Natl. Lab. Host: Bob Sweet
Wednesday September 16 1:00 pm	Structure of the KH RNA-binding domain and progress in the RNA-bound structure determination via MAD Hal A. Lewis, The Rockefeller University Host: Bob Sweet
Thursday September 17 3:45 pm	Molecular architecture of Borrelia burgdorferi Implications for Lyme disease pathogenesis: Justin Randolf, University of Texas, Southwestern Medical Center Host: John Dunn
Wednesday September 23 1:00 pm	Crystallographic studies of the small domain of calpain Pawel Grochulski, Biotechnology Research Institute, NRC, Canada Host: Bob Sweet
Monday September 28 3:45 pm	Antibody responses to the paralogous plasmid-encoded Borrelia burgdorferi Dip (ORF-E) protein Wolfram Zueckert, Univeristy of California, Irvine Host: Cathy Lawson
Tuesday October 6 noon	Solvation Effects on Protein Folding, Binding, and Design: Exploring the Electrostatic Balance Bruce Tidor, Department of Chemistry, MIT Host: Wally Mangel
Friday October 30 11:00 am	ESI-MS Characterization of DNA Repair Complexes Charles Iden, Pharmacology Department, SUNY-Stony Brook Host: Carl Anderson
Thursday November 5 3:45 pm	ATM-Dependent Regulation of p53 by DNA Damage Thanos Halazonetis, Molecular Genetics Department, Wistar Institute Host: Carl Anderson
Thursday November 19 3:45 pm	Formation and Inhibition of Intracellular Heme Crystals by the Malaria Parasite P. falciparum David Sullivan, Johns Hopkins University Host: Michael Becker
Thursday December 3 3:45 pm	Adaptation of Microbial Communities to Environmental Stress: Examining the Incidence of Horizontal Gene Transfer Barth F. Smets, University of Connecticut, Storrs Host: John Dunn
Tuesday December 8 3:45 pm	Time-Resolved Structural Biology: Folding of Large RNAs Mark R. Chance, Department of Physiology & Biophysics and Biochemistry, Albert Einstein College of Medicine Host: F. William Studier
Thursday December 17 3:45 pm	Molecular Responses to Gentoxic Stress - A Functional Genomics Approach Using cDNA Microarray Albert J. Fornace, Laboratory of Molecular Pharmacology, National Cancer Institute Host: Carl Anderson

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